NODULAR DYSTROPHY OF THE TRABECULAR MESHWORK

Nodular Dystrophy of the Trabecular Meshwork.

THE description of the microscopic structure of individual trabecular fibres given by Salzmann (1912) has been accepted for many years, and it is only as a result of recent electron microscopic studies that his classical concepts have had to be modified. The principle modification concerns the finer structure of the "clear" zone which lies beneath the trabecular endothelium and surrounds the ce...

Calf Trabecular Meshwork

Superoxide dismutase and catalase activities have been measured in cell-free extracts of calf trabecular meshwork, and for comparison, in calf iris, retina, lens, liver, and erythrocytes. Gel electrophoresis has been used to identify isozymes of each enzyme. The superoxide dismutase and catalase activities per milligram wet weight of calf trabecular meshwork, 0.184 and 0.884 U/mg wet wt, respec...

Trabecular meshwork and outflow

Core Concepts • iOP elevation results from increased outflow resistance in the outflow pathways: the trabecular meshwork (TM) and the uveoscleral pathway. • steady-state iOP is found in normal eyes where iOP builds up in response to inflow of aqueous humour to the level sufficient to drive fluid across the resistance of the outflow pathways. • in most glaucomatous eyes, the resistance of the ou...

The Cytoskeletal Network of the Trabecular Meshwork

Two-photon imaging of the trabecular meshwork

PURPOSE To image the trabecular meshwork (TM) in its native unfixed state using a non-invasive, non-destructive technique. METHODS Two-photon microscopy (2PM), including two-photon excitation fluorescence (2PEF) and second harmonic generation (SHG), was used to image flat-mounted trabecular meshwork samples from human cadaver eyes. Multiple images were analyzed along the tissue axis (z-axis) ...